Aleksandra Ellert-Miklaszewska PhD

Research interest:

My current research is focused on brain tumor cells-derived signals, which re-program infiltrating immune cells including microglia into tumor supportive cells. This mechanism of modification of tumor microenvironment significantly contributes to glioma pathology.

Grants:

(led as the Principal Investigator during last 5 years)

• 2014/15/B/NZ3/04704 National Science Center The role of NFAT (nuclear factor of activated T cells) and GM-CSF (granulocyte/macrophage colony stimulating factor) signaling in glioma pathogenesis. (2015-2018)

• POMOST/2012-5/4 Foundation for Polish Science Glioma-derived MFGE8/Lactadherin as a factor that instructs microglia to orchestrate tumor growth (2012-2015)

• N-N301 530238 National Science Center Identification of factors and signaling pathways modulating microglia in the initiation of inflammation (2010-2013)

Awards:

• Price of Polish Biochemical Society and Merck Sp. z.o.o. for the best PhD thesis in Biochemistry in 2007.

• IIo Price of the Chancellor of Medical University of Warsaw for scientific achievements, October 2006

• IIIo Price of the Chancellor of Medical University of Warsaw for scientific achievements, June 2008

• Award of Neurobiology Committee PAS, Department II of Biological Sciences, for the group of prof. Bozena Kaminska for the series of publications “Molecular mechanisms of regulation of tumour cells invasiveness and viability”. December 2008

• Award of the Department II of Biological and Agricultural Sciences PAS, for the group of prof. Bozena Kaminska for the discovering of the new mechanisms of cancerogenesis, crucial for the pathobiology and therapy of malignant gliomas. December 2014

• 3rd price ELSO Poster Award at ELSO Meeting, Nice, France September 2008

• 1st Price for Poster presentation at XLV Meeting of Polish Biochemical Society, Wisla, September 2010