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Professionally, passionate with molecular mechanisms of protein quality control in neurodegenerative diseases, sterile inflammation and in import of mitochondrial precursor proteins. Currently, I am happy to research the heterogeneity of the immune system cells in the glioblastoma microenvironment.
Privately, a lover of climbing, hiking, baking cakes and playing the violin.
List of publications:
Anna Wilkaniec, Anna M. Lenkiewicz, Emilia Murawska, Henryk Michał Jęśko, Magdalena Cieślik, Carsten Culmsee, Agata Adamczyk, „Exogenous alpha-synuclein evoked parkin downregulation promotes mitochondrial dysfunction in neuronal cells. Implications for Parkinson's disease pathology”. Frontiers in Aging Neuroscience (2021), doi: 10.3389/fnagi.2021.591475.
Anna M. Lenkiewicz, chapter 12 „Epidermal Stem Cells”, Stem Cells, Advances in Experimental Medicine and Biology 1201, © Springer Nature Switzerland AG 2019, M. Z. Ratajczak (ed.), 239-259.
Lenkiewicz A, Bujko K, Brzezniakiewicz-Janus K, Xu B, Ratajczak MZ. „The Complement Cascade as a Mediator of Human Malignant Hematopoietic Cell Trafficking”. Front Immunol. (2019) 7;10:1292.
Lenkiewicz AM, Adamiak M, Thapa A, Bujko K, Pedziwiatr D, Abdel-Latif AK, Kucia M, Ratajczak J, Ratajczak MZ. „The Nlrp3 Inflammasome Orchestrates Mobilization of Bone Marrow-Residing Stem Cells into Peripheral Blood”. Stem Cell Rev. 2019 15(3):391-403.
Adamiak M, Lenkiewicz AM, Cymer M, Kucia M, Ratajczak J, Ratajczak MZ. „Novel evidence that an alternative complement cascade pathway is involved in optimal mobilization of hematopoietic stem/progenitor cells in Nlrp3 inflammasome-dependent manner”. Leukemia. 2019, doi: 10.1038/s41375-019-0530-9.
Ratajczak MZ, Adamiak M, Thapa A, Bujko K, Brzezniakiewicz-Janus K, Lenkiewicz AM. „NLRP3 inflammasome couples purinergic signaling with activation of the complement cascade for the optimal release of cells from bone marrow”. Leukemia. 2019 33(4):815-825.
Anna Wilkaniec, Anna M. Lenkiewicz, Grzegorz A. Czapski, Henryk Jęśko, Wojciech Hilgier, Robert Brodzik, Carsten Culmsee, Agata Adamczyk. "Extracellular alpha-synuclein oligomers induce parkin S-nitrosylation: relevance to sporadic Parkinson's disease etiopathology". Molecular neurobiology (2018): 1-16.
Jęśko, Henryk, Anna M. Lenkiewicz, Agata Adamczyk. "Treatments and compositions targeting α-synuclein: a patent review (2010-2016)." Expert opinion on therapeutic patents 27.4 (2017): 427-438.
Dominiak, A., Wilkaniec, A., Jęśko, H., Czapski, G. A., Lenkiewicz, A. M., Kurek, E., Wroczyński, P., Adamczyk, A. (2017). „Selol, an organic selenium donor, prevents lipopolysaccharide-induced oxidative stress and inflammatory reaction in the rat brain.” Neurochemistry International (2017).
Lenkiewicz, Anna Magdalena, et al. "Potent effects of alkaloid-rich extract from Huperzia selago against sodium nitroprusside-evoked PC12 cells damage via attenuation of oxidative stress and apoptosis." Folia Neuropathologica 54.2 (2016): 156-166.
Gąssowska, M., Czapski, G. A., Pająk, B., Cieślik, M., Lenkiewicz, A. M., & Adamczyk, A. „Extracellular α-synuclein leads to microtubule destabilization via GSK-3β-dependent Tau phosphorylation in PC12 cells.” PloS one (2014), 9(4), e94259.
Suwińska, Aneta, Anna Magdalena Lenkiewicz. "Pierwotne linie komórkowe w zarodku myszy - źródło zarodkowych komórek macierzystych." Postępy Biologii Komórki 37.1 (2010): 3-21.
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